YOURS is an interesting post. I have been loading the 45ACP for over 45 years with all the traditional propellents, Bullseye, Unique [ Hodgdon's UNIVERSAL now] etc. Back then AA and all their products were not even a gleam in a chemical engineers eye.
Since then I have used ALL the AA propellents in various calibers [ I load for a 135 of 'em at last count ] and have several favorite loads with AA5, AA7, AA9, XMP5744 etc. AA5 in particular has been outstanding in 38SPL+P-158gr SWC loads and the top load shoots very well in ALL my 38SPL and 357MAG sixguns, a most pleasing situation indeed !! AS a matter of fact I was looking for one 38+P load that shot well in all my guns when I found it in AA5, no other propellent in that search was even close.
I've never given a thought to trying AA5 in the 45ACP [ 45AR too...maybe ??] and it does look to be darned interesting. The other side of this coin is now almost ALL of my 45ACP shooting is with a COLT SAA 45ACP sixgun which puts all the fired brass in my waiting hand...imagine that ?!!!