Not just no, but HELL NO! The .44 mag case is about 1/8" longer than the .44 Special and is supposed to prevent magnum rounds from going in a Special gun, but once in a blue moon a magnum round can be forced in. A kaboom is the likely result.
First of all WHY would you want to shoot .44 MAG in a Colt SAA ? When you can buy either a SA or DA Ruger or S&W in 44 mag for less than $550. You can shoot 44/40 with a new cylinder in the 44 special. For a nice light load there is the .44 Russian. You do not need to change anything to shoot the .44 Russian.
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