Well, I'm glad everyone here has an open mind.
This all started with "I wonder if I could...". I was shooting my 8" .22 Trooper MKIII one day, thinking how cool it would be to have a .22 Python. Nothing wrong with the Trooper, but the barrel of a Python is just so much better looking (my opinion). I started thinking about modifying a Python, but that quickly became expensive. So you all know what came next...
I had it all in my head, I just needed a competent machinist/gunsmith to make it real. I took an 8" Python barrel that I bought from a forum member, my Trooper MKIII, and a 3/8" .22 barrel liner and headed to the gunsmith. We decided the best path forward would be to turn the liner to snugly fit in the .357 bore. Cut the existing threads off since the are a diferent size and the thread post is much longer. Back bore and thread the Python barrel to accept a plug/adapter that would screw into the barrel and be locktighted in place, the other end is threaded to match the Trooper. Once that was done, the liner was glassed into place. Crown, forcing cone, re-barrel, headspaced... Tah Dah!!!
Only Colt part that was harmed in this project was a Python barrel... The Trooper could be put back to original any day, but it will likely not as long as I own... Too much fun!