While I agree with dfw that each gun is an island unto itself, in my opinion, the earlier the gun, the better the quality. My Pre-War National Match is worlds better in fit and finish than my secretary's recent Gold Cup.
I hate to throw cold water on the poster's conclusion that 1980s Pythons will be as nice as 1960s or 1970s Pythons, but, in my opinion, GENERALLY, I have observed that the polishing on UAW-made 1980s Colts is inferior to earlier, and, in most cases, later Colts. The flats are often not flat, the corners are often rounded, and screw holes are sometimes even "pulled" or "dished" out on many of that vintage.
If the poster was able to examine the Python in question close enough to get the serial number, then I would think the quality should have been readily apparent. If this particular gun looks acceptable to the buyer, then it is of sufficient quality to satisy. However, it will not likely measure up to 1950s or 1960s quality. I have first year production Pythons for all three of the original barrel lengths, 6-inch, 4-inch and 2.5-inch, and they are better than most anything made a decade later.
If the poster wants the best Python, then a gun from the 1950s or 1960s probably will be the only choice.
I agree with dfw that some of the current Colts are very nicely made.