That's an odd one.
It can be tough to diagnose when the problem is so intermittent.
Off hand, I can't think of anything that would slow hammer drop but not do it every time.
As said above, if something is out of order with the action, the hammer DA strut can catch or bump on the trigger and either stop or slow hammer fall.
If the action is fouled with impacted gunk, or some debris is floating around it might cause this.
You might remove the grips and spray a good lubricant into the action to flush it out and dissolve old lubricant and fouling.
Let soak over night then drain, shake, and wipe off the excess.
See if that has any effect.
If not, your best option is to send it in to Colt for a correct diagnosis and repair back to factory specifications.
Again, no local gunsmiths. Pythons are simply too valuable to risk with someone who probably doesn't really "understand" the old Colt action and can cause real damage.