Michael, the 2 rear sights are far too dissimilar to interchange. They are not even close to the same length nor is the pin that holds them in place anywhere close to the same relative position. I have confirmed this on a Blackhawk, GP100 and a Redhawk against a Python.
WS23 - Thanks for the detailed and visual-aid enabled responses!!! What do you think about sight-blade compatibility? For example, is it conceivable that a blade from a Ruger sight would fit into a Python? Its hard for me to tell from the photos.