Less than a box of .44 spl. through my 3rd generation SAA and the timimg went off. That, combined w/ the worst trigger of any gun I own, makes me very unhappy. But I have no intentions of ever getting rid of it. Sick.
An action job is almost mandatory on the new SAA's, but they are very satisfying after they've been smoothed up. My favorite shooters are a slicked up .44 Special 3rd generation, and a New Frontier 3rd generation.
I don't know about the timing, I've never had such a problem in the dozen or so Colt single actions I've owned.